glutathione for perimenopause is under tight homeostatic control. Too much won't work and too little won't either., If you get too much into your cell, your body will push it out. It keeps a very specific amount in Glutathione with Cofactors

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Psychiatry 19 , 978985 (2014)

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With a complex molecule like glutathione, high bioavailability is the difference between a wasted effort and a successful wellness routine