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The induction of this process may be associated with the growth factors produced by vascular endothelial cells, such as platelet-derived growth factor and vascular endothelial growth factor [27]

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Major Symptoms of Redworms in Horses Loss of condition Severe weight loss Anemia Distended stomach Stare or dull coat Diarrhea Colic Fluid swellings in the legs, around the sheath, or on the stomach Reducing the horses ability to absorb nutrients Your horse may become a chronic bad doer, and in some cases, the infestation may be fatal

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This is just one of many hardships Ruth endured through childhood