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Conclusion The present investigation revealed that the administration of PET-NaPs causes significant histological alterations and oxidative stress-induced harm in mices cerebral tissue

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Animal models, while more physiologically complex, are expensive, ethically constrained, and often poorly predictive of human pathophysiology, contributing to translational failure (56)

Los estudios de toxicidad aguda y subcrnica en la rata no han revelado toxicidad significativa a las dosis teraputicas estudiadas

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