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This addresses the vascular component of nerve damage that is particularly relevant in diabetic neuropathy where microangiopathy starves nerves of oxygen and nutrients

Gemcitabine induces CAFs to secrete exosomes containing miR-3173-5p, which inhibits the expression of ACSL4, thereby decreasing PUFA binding to phospholipids and enhancing resistance to ferroptosis in PDAC cells [41, 42]

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It also has anti-inflammatory properties and phosphorylation-suppressing properties of tau protein in the hippocampus (Machado et al

Another important observation of that period was made by Goldberg, who studied protein turnover in skeletal muscle of hypophysectomized rats with 3H-leucine tracer techniques