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However, the increase in mGluRs-dependent signaling in the mouse model of FXS was not confirmed in human-based models, and clinical trials with mGluR inhibitors failed to produce a therapeutic effect in FXS patients [331]

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Ionescu M, Frohman LA Pulsatile Secretion of Growth Hormone (GH) Persists during Continuous Stimulation by CJC-1295, a Long-Acting GH-Releasing Hormone Analog

Real-world persistence and adherence to ofatumumab versus other self-injectable disease modifying therapies (DMTs) in patients with multiple sclerosis (MS)