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This decrease was more pronounced when adipocytes from HSL-null mice were utilized, a finding that suggests cooperativity exists between the two enzymes, and indeed, a synergistic effect has been observed on lipolysis when cells are cotransfected with both desnutrin/ATGL and HSL (144)

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By influencing these neurotransmitters, peptide DSIP can promote slow-wave sleep, regulate sleep-wake cycles, and modulate stress responses

doi: 10.3389/fonc.2023.1089115 72 XieCZhuJJiangYChenJWangXGengSet al