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This mechanism provides a strong rationale for combining NO-based therapies with checkpoint inhibitors such as anti-PD-1/PD-L1 to overcome hypoxia-induced immune resistance in CRC (143)

Antioxidants 10 (11), 1696

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Within experimental models, researchers frequently investigate DSIP in relation to neuropeptide signalling networks and intracellular communication mechanisms

For Ube2d3-His 6 , the gene was cloned into pGEX-4T1 for expression as an N-terminal GST fusion with a TEV cleavage site