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The metabolism and clearance of both components may be affected by significant liver disease, and patients with severe hepatic impairment should be monitored closely if treatment is deemed necessary
The dosage and administration of Cyanocobalamin are determined by a healthcare provider based on the patients age, medical condition, and the severity of the B12 deficiency
With a 1 mg/ml reconstituted vial, common starting doses translate directly to syringe markings: a 0.25 mg starting dose = 0.25 ml = 25 units on a U-100 insulin syringe
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