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Description

Leukemia 36 , 10881101 (2022)

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Over time, the genome becomes increasingly dysregulated: DNA regions that should be silent become noisy, protective genes are switched off, and chromatin, the scaffold of DNA wrapped around histones (imagine them like packaging bundles), becomes condensed and brittle, losing its flexibility

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from about 1000 to about 1,000,000 centipoise

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