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A redox-triggered bispecific supramolecular nanomedicine based on peptide self-assembly for high-efficacy and low-toxicity cancer therapy

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In adipocytes, NNMT inhibition elevates NAD and SAM and suppresses de novo lipogenesis in a concentration-dependent manner, consistent with on-target activity [13]

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This is in contrast to a previous study that demonstrated that melatoninbetaine exerted potent anti-inflammatory actions in rodents with cisplatin-induced nephrotoxicity (Al Zaabi et al., 2021a)