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2.3 Data analysis All data were analyzed in Osprey software package (version 2.4.0)(Oeltzschner et al., 2020), using consensus-recommended pre-processing(Choi et al., 2021) and linear-combination modeling

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2016 Jun;46(6):747-9

Specifically, intestinal dysbiosis results in the loss of the gut barrier integrity that allows lipopolysaccharide (LPS) translocation from bacteria into circulation where LPS acts as a ligand-dependent toll-like receptor 4 (TLR4) stimulator initiating downstream signaling cascades amplifying the systemic inflammatory cascade (Longo et al., 2024)

Argireline Argireline targets expression lines by relaxing muscle signaling