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Individuals are encouraged to report adverse reactions to unlicensed products via the MHRA's Yellow Card scheme (yellowcard.mhra.gov.uk), which helps regulators identify emerging safety signals
(2022) found that CHAC1 overexpression in various breast cancer cells is often driven by hypomethylation of its promoter region, particularly in tumors harboring mutant TP53 (Mehta et al., 2022)