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Proteins that have undergone lactylation are inclined to engage in the modulation of neuronal activity, which can exacerbate neuronal damage and lead to impaired brain function [46]

Water and sodium retention Acute: Increased fluid volume causes increased cardiac output, which causes increased blood pressure (BP)

By inhibiting BAFF, Belimumab reduces abnormal B-cell activity, a central feature of SLE

The four components span distinct structural classes and non-overlapping pathway layers signaling, ECM remodeling, cytoskeleton, and inflammation

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Validation revealed elevated GSS (2-fold) and its enzymatic product glutathione (1.7-fold) in tear fluid of amyloid PETpositive participants