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This outcome reinforces how difficult it is to outperform established incretin leaders and underscores the need for optimized dosing and rigorous blinded trials to fully define CagriSemas role in obesity care

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Red flag symptoms requiring immediate evaluation include unintentional weight loss over 10 pounds, persistent vomiting, black or bloody stools, or difficulty swallowingthese may indicate ulcers, inflammatory bowel disease, or malignancy

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