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European neurology , 23 5, 364-71

Post-stroke blood-brain barrier disruption and poor functional outcome in patients receiving thrombolytic therapy

La Rocca, C., Carbone, F., Longobardi, S

3.1.2 Mechanism of lipid peroxidation-mediated ferroptosis involved in ischemic stroke As outlined, lipid peroxidation, particularly the conversion of PUFAs in the phospholipid bilayer to L-OOHs, is a crucial mechanism of ferroptosis and plays a significant role in the development of IS

doi: 10.1186/1471-2164-13-274 115