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Table 2 Mechanisms of action of CPM

H.DencherN

Stop and speak with a clinician if you see severe redness, swelling, fever, or a rash

May, Qu & Morrow, 1996

The imbalance in intestinal microbiota alters the tight intercellular junctions (TJ) that allow access to pathogens and toxins (bacterial lipopolysaccharides, LPS)

Interestingly, the transcription factor c-Myc (involved in tumorigenesis in several cancers) can both promote proline (and also serine [101]) synthesis and inhibit proline breakdown [102], contributing to the protumor effects of proline