S100B and APP promote a gliocentric shift and impaired neurogenesis in Down syndrome neural progenitors
White Americans were the least hopeful, with 43% believing a cure for Alzheimer's disease was plausible in this timeframe
The blue colour comes from the coordinated copper(II) ion it is the d-d electronic transition of Cu(II) in the peptide complex, the same physics that makes copper sulphate solutions blue
Media Attributions Figure 11.1.1 Steven Earle, CC BY SA 4.0, after Water Cycle by Ingwik, CC BY SA 3.0, via Wikimedia Commons, Figure 11.1.2 Steven Earle, CC BY 4.0 Figure 11.1.3 Modified by Steven Earle, from Mackenzie River with Heavy Sediment Load by Pierre Markuse, 2018, CC BY 2.0 via Flickr,
Renal clearance of peptides varies with glomerular filtration rate, and no dose-adjustment guidance exists because no human pharmacokinetic study has been completed
1-10 mg/kg in animal studies KPV studies: 100 micromolar oral concentrations in colitis models