BX795 Pack Size:10 mM * 1 mL in DMSO logKpot(NO3/Br):-1

logKpot(NO3/Br):-1

an Enhanced Dual APRIL/BAFF Antagonist that Modulates B Lymphocytes and Pathogenic Autoantibodies for the Treatment of Lupus and Other B Cell-Related Autoimmune Diseases: L

is challenging

AQC-derivatized polyamines display excitation/emission maxima of 248/398 nm

because of their unique structures

BX795 Pack Size:10 mM * 1 mL in DMSO logKpot(NO3/Br):-1BX795 is a potent and selective inhibitor of PDK1, with an IC50 of 6 nM. BX795 is also a potent and relatively specific inhibitor of TBK1 and IKK, with an IC50 of 6 and 41 nM, respectively. BX795 blocks phosphorylation of S6K1, Akt, PKC, and GSK3, and has lower selectivity over PKA, PKC, c Kit, GSK3 etc. BX795 modulates autophagy.