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Loren Pickart, the biochemist who first characterized GHK from human plasma in 1973, has noted: "The peptide itself is extraordinarily safe at physiological concentrations

It has been studied for its remarkable regenerative properties and its ability to support the body's natural healing processes

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Nevertheless, certain conditions can impact the absorption or intake, hence often leading to deficiency, for example, pernicious anemia or if the individual follows a vegan diet

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Lambadiari V, Pililis S, Lampsas S et al (2025) Endothelial function and matrix metalloproteinase 9 (MMP9) in women with polycystic ovary syndrome (PCOS)