Among the genes downregulated in response to GSTO1 siRNA, coagulation factor III ( F3 ), thrombospondin 1 ( THBS1 ), cysteine-rich angiogenic inducer ( CYR61 ) and bone morphogenetic protein 4 ( BMP4 ), related to blood coagulation and blood vessel morphogenesis, were markedly decreased (Supplementary Table 11)
(2024) 20:e2309597
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Bero AW, Yan P, Roh JH, Cirrito JR, Stewart FR, Raichle ME, et al
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SREBP-1a has been identified as a potent transcriptional activator, with the capacity to promote both fatty acid and cholesterol synthesis