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On the other hand, human data are highly impactful in this context, as reduced levels of clinical risk markers predictive of tobacco-related morbidity and mortality due to the complete switch to alternative inhalable nicotine delivery systems, are the ultimate evidence of harm reduction

Effective control programs against tobacco smoking should be further developed and implemented in Korea to reduce the smoking-related cancer burden

Of the total participants, 10.8% were smokers at baseline, 38.7% were former smokers, and 50.5% had never smoked

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