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DISCUSSION The goal of this study was to develop an AnglV-derived molecule that retained the pro-cognitive/anti-dementia activity of AnglV and Nle'-AnglV but possessed improved pharmacokinetic properties, thus allowing it to penetrate the BBB in sufficient quantities to reach therapeutic levels in the brain
COA verified per batch
Most current therapeutic candidates for NDDs face challenges in crossing the bloodbrain barrier, substantially limiting their clinical efficacy (Ross and Poirier, 2004)
Nat Commun 10, 5536
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