MinuteTM Protein Solubilization Reagent for MS Denaturing Protein Tazemetostat inhibits the activity of

Tazemetostat inhibits the activity of human polycomb repressive complex 2 (PRC2)-containing wild-type EZH2 with a Ki value of 2

A notable drawback of the conventional TCA/acetone precipitation approach is its diminished efficacy when dealing with samples featuring low protein concentrations

Solubilized proteins are denatured due to the presence of an anionic detergent (SDS)

Many affinity-based methods require harsh elution conditions that may affect the activity of isolated proteasomes and limit certain downstream applications

Neurons are highly interconnected

MinuteTM Protein Solubilization Reagent for MS Denaturing Protein Tazemetostat inhibits the activity ofThis reagent is formulated for dissolving protein and organelle pellets using Minute kits from Invent Biotechnologies or similar products of other manufacturers. Solubilized proteins are denatured due to the presence of SDS and can be used for trypsin digestion and for subsequent mass spectrometry analysis.