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The mechanism through which the peptide might alter in-vivo melatonin measurements remains uncertain

doi: 10.3389/fonc.2026.1751474 Received 21 November 2025 Revised 14 January 2026 Accepted 03 February 2026 Published 18 February 2026 Volume 16 - 2026 Edited by Dana Kristjansson, Norwegian Institute of Public Health (NIPH), Norway Reviewed by Feng Wang, Affiliated Hospital of Nantong University, China Bingran Yu, Shandong University, China Updates Copyright 2026 Pathania and Osna

IGF-1-LR3 is a modified, longer-acting version of insulin-like growth factor 1 (IGF-1), a peptide associated with the body's natural growth, recovery, and tissue-repair signaling pathways