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Yung KL, Xu Y, Kang C, Liu H, Tam KF, Ko SM, et al

Future research and clinical trials will play a crucial role in optimizing the use of HDACi, elucidating resistance mechanisms, and identifying the most effective combinations to maximize patient benefit

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The pKas of the active Cys in Grxs were generally between 7 and 8, while Cys in proteins which are modified by GSH were between 10 and 11