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It affects approximately 4.6% of the US population, with higher rates in women (about 10% in women over 60 years) (Wyne et al

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Access this article Similar content being viewed by others Data Availability The authors confirm that the data supporting the findings of this study are available within the article

Recombinant human KAI1/CD82 attenuates M1 macrophage polarization on LPS-stimulated RAW264.7 cells via blocking TLR4/JNK/NF-B signal pathway

20 Thus, by definition, astroglial reactivity is always secondary, being a response of astroglial cells to a pathological process