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doi: 10.1111/and.2019.51.issue-1 36 BischoffNSde KokTMSijmDTvan BredaSGBriedJJCastenmillerJJet al

In consequence, acylcarnitines constitute an appreciable component of the tissue carnitine pool, and tissue and plasma concentrations of carnitine and acylcarnitines are together maintained within relatively narrow limits by a variety of mechanisms, which influence in turn innumerable aspects of carbohydrate and lipid metabolism, including the regulation of insulin secretion by pancreatic -cells and the determination of tissue insulin sensitivity

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This significantly extends their shelf life, allowing them to remain stable for months to years

That research is on a specific prescription formulation rather than Aqualyx itself, so it is fair to say the class is well studied even though Aqualyx is mostly backed by real-world clinical use