doi: 10.4161/oxim.3.4.12858
Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing sp1 glycosylation
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The bone volume (BV)/total volume (TV) of talus bone was calculated with software (Version: 6.5-3, SCANCO Medical AG, Switzerland) by evaluating and analyzing the three-dimensional region of interest (ROI)
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Metabolite concentrations were normalized to the concentration of water calculated from unsuppressed water spectra, since variations in water content within the sample are expected to be much smaller than the variations in the metabolite level [52]