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Phorbol 12-myristate 13-acetate [PMA] Pack Size:25 mg It contains two non-coded amino

SKU: 68252642634

4.6
USD214.00 USD253.00

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Description

It contains two non-coded amino acid residues (Aib

Many methods are tedious and time consuming

which is involved in the maintenance of peripheral tolerance to self-antigens

Selective cell permeable and irreversible MALT1 inhibitor

cell culture supernatant or ascites and for Immunoprecipitation and Co-Immunoprecipitation of antigens from cell or tissue extracts

Phorbol 12-myristate 13-acetate [PMA] Pack Size:25 mg It contains two non-coded aminoPMA TPA is the most commonly used phorbol ester. Binds to and activates protein kinase C (PKC) at nM concentrations. Induces cell growth arrest through a variety of pathways including the mitogen activated protein kinases (MAPKs), p38 and c Jun N terminal kinase (JNK) pathways mediated by cyclin dependent kinase (CDK) inhibitors such as p21WAF1 CIP1, p27KIP1, p15 and p16. Potent mouse skin tumor promoter. Promoter of inducible NOS (iNOS; NOS II).

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