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She didn't have any trouble scaling back -- she smoked more out of boredom and habit than nicotine addiction, she says -- but she has found her social smoking at bars surprisingly hard to kick

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In contrast, the Cys349 to Tyr substitution alters the subcellular localization of ToMV replication proteins, such that replication proteins of L 11 tend to be membrane-bound, which causes a shortage of replication proteins in the soluble fraction

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