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It binds toxic metabolites so they can be excreted through bile or urine

In some embodiments, the otic composition or formulation comprises less than 1% by weight of C1-C4 alcohols or C1-C4 glycols

Depade), prevents the reinforcing effects of alcohol by interfering with its enhancement of the mesolimbic DA transmission [111] strengthening the potential of caffeine, and more specifically of A2 A R antagonists, for future development of preventive/therapeutic strategies for AUD

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