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Cancer cells typically maintain high levels of NADP, primarily providing the reducing power for anabolic reactions and redox balance, crucial for sustaining their rapid growth and providing protection against oxidative stress

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Indeed, short-term glutaminolysis induces mTORC1 lysosomal translocation and activation via the Rag GTPase, then inhibiting autophagy and promoting cell growth [88]

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The peptide directly stimulates angiogenesis by promoting endothelial cell migration and proliferation while simultaneously modulating ERK1/2 signaling cascades that control cell growth, migration, and tissue remodeling