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Front Plant Sci 7:301

Cytokine-mediated host responses during schistosome infections

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PMID: 27880008

First, it increases satiety hormones like peptide YY (PYY) and reduces ghrelin, often called the 'hunger hormone,' which normally rises before meals to trigger eating

Moreover, ALA exerts antioxidant effects via a dual mechanism: (i) rapid redox-cycling between its disulfide (ALA) and dihydrolipoate (DHLA) forms, which directly quenches ROS without transcriptional activation, and (ii) secondary upregulation of the Nrf2 pathway and suppression of NF-B nuclear translocation (Ghibu et al., 2009)