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Barth SW, Lehner MD, Dietz GPH, Schulze H

In cell-based assays B7-33 behaves as a functionally selective (biased) agonist, preferentially engaging the pERK1/2 signalling arm with comparatively weaker cAMP accumulation relative to native relaxin-2

Human use is not FDA-approved, but accumulated clinical experience is reassuring: Common and mild Injection site reaction: mild redness, swelling, tenderness - resolves within hours

Contaminants : The presence of proteases, bacteria, or other contaminants can lead to peptide breakdown

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