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To exemplify, aripiprazole and risperidone have proven useful for controlling irritability, aggression and emotional dysregulation, compared to placebo (Salazar, et al., 2023)

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22 Continuous IV infusion is recommended at a loading dose of 150 mg/kg IV in 200 mL D5W infused over 60 minutes followed by a maintenance dose of 50 mg/kg over 4 hours, followed by a second maintenance dose of 100 mg/kg in 1,000 mL D5W administered over 16 hours