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194 The pathophysiology is thought to involve ischemia due to microangiopathy and metabolic disturbances

broader NO-system interplay summarized in review (Sikiric 2014)

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2) Joint Pain and Cartilage Damage: Arthritis (Osteoarthritis and Rheumatoid Arthritis): While direct human studies on arthritis are limited, BPC-157s ability to promote collagen production and reduce inflammation suggests potential benefits for managing arthritis symptoms (8, 9)

The most common adverse effects observed in clinical trials were upper respiratory tract infections, nasopharyngitis, headaches, and high blood pressure