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Clody, P.W

Deleting the GPX4 gene or treatment with GPX4 inhibitors (e.g., RSL3, ML162, and ML210) induces lipid peroxidation and concomitant ferroptotic cell death in T cells in vitro (Matsushita et al., 2015

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Your primary defense against that oxidative damage

Among all the engineered strains, the strain W303-1b/FGP with three biosynthetic pathways showed the highest GSH producing capacity and improved the intracellular GSH concentration by 2.19-fold compared with W303-1b (Table 3

Table 1 Main studies on the role of reduced glutathione (GSH) treatment in patients with metabolic liver disease