doi: 10.1016/j.bcp.2010.12.014 228 GusevaNVRokhlinOWGloverRACohenMB
Even if cysteine S -conjugate -lyase is responsible for the synthesis of the highly reactive and cytotoxic thiol version of cisplatin ( Figure 1 ), the activation of cisplatin into a nephrotoxin relies on the three previous steps of the classical mercapturic acid pathway involving GSTs (GSH conjugation), GT (production of CisPt-cys-glu) and dipeptidase (production of CisPt-cys
The peptide calculator and reconstitution calculator help with the math
Acta 1840 , 951957 (2014)
Did you know that with our Healthy Awards program, you can earn points towards Cash Back Awards for every dollar you spend
Drug preparation For phase I and II, an injectable formulation of sodium benzoate (SB) (Spruyt Hillen BV, IJsselstein, Netherlands) and sodium phenylacetate (SPA) (Sigma-Aldrich, Steinheim, Germany) were prepared by the Pharmacy Department of the Faculty of Veterinary Medicine, Utrecht University
