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People can become deficient when they are not eating enough vitamin B12 rich foods, or their bodies may struggle with absorbing the vitamin

However, there are certain conditions in which vitamin B12 cannot be absorbed, for example, due to dietary insufficiency, malabsorption, or lack of intrinsic factor, hepatic stores are depleted, and deficiency ensues

The Phase IIb clinical trials failed because AOD 9604 did not produce a statistically significant amount of weight loss in obese patients compared to a placebo

In addition, farmers often supplement their animal feeds with additional vitamin B12

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