Not everyone on TRT experiences hair thinning
Interestingly, activation/inactivation of glucocorticoids and 11-oxygenated androgens work in an antiparallel manner, with the 11-hydroxy derivative being the active glucocorticoid [74,75], while the 11-keto androgens are more potent than their 11-hydroxy counterparts [76]
Oily or Acne-Prone Skin Salicylic Acid Unlike glycolic acid, salicylic acid decreases sebum in the skin
Dixon's group demonstrated that the GSH exporter MRP1 sensitizes HPA1 erastin-treated cells to ferroptosis and concordantly, MRP1 inhibition leads to a retention of GSH and leads to ferroptosis resistance (58)
J Am Chem Soc 133:1155711571
Excessive shortening triggers persistent DNA damage response or genomic instability, causing cellular senescence, and is also strongly linked to lifespan (Whittemore et al., 2019