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10.1126/science.1225152 152 NajmanovI.VopralovM.SasoL.MladnkaP

When you use vitamin C or vitamin E, they eventually become "spent." Glutathione can help bring them back to their active state

189 Further, ME1 treated with the inhibitor (piperazine-1-pyrrolidine-2,5-dione) has little effect on normal rat intestinal epithelial cells but strongly suppresses human CRC cell growth by targeting ME1 NADP + -binding site and reducing the NADPH level

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