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Briefly, at 4 C, equal volumes of HiBiT-N VLPs and hACE2-LgBiT EVs were mixed with nanoluc substrate (catalog # N2420, Promega, USA) and trypsin (Sigma-Aldrich, USA

Gamma-oryzanol alleviates intervertebral disc degeneration development by intercepting the IL-1/NLRP3 inflammasome positive cycle

3c,d and Supplementary Fig

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