Basic cleanliness rather than strict sterility suffices, though clean handling always preserves product quality better
Dosage: Individualize dosing based on the patients specific medical condition and B12 concentration level in the body
History [edit] Descriptions of deficiency effects [edit] Between 1849 and 1887, Thomas Addison described a case of pernicious anemia, William Osler and William Gardner first described a case of neuropathy, Hayem described large red cells in the peripheral blood in this condition, which he called "giant blood corpuscles" (now called macrocytes), Paul Ehrlich identified megaloblasts in the bone marrow, and Ludwig Lichtheim described a case of myelopathy
The best results usually come from knowing the cause first, then sticking with a plan long enough to let it work
Moreover, skeletal muscle injury models have suggested a beneficial effect not only for disturbances that occur as a result of direct trauma but also for systemic insults including hyperkalamia and hypermagnesia
Standard dosing ranges from 1-2mg daily or 2-3mg several times weekly