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However, in some cases, your doctor may recommend a B12 shot or injection

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The 2004 Valdatta double-blind RCT in Current Medical Research and Opinion enrolled 26 patients undergoing skin graft donor-site surgery, randomized to PDRN or placebo

Monti and colleagues in Uruguay ran a double-blind crossover of 25 nmol/kg over four nights and found that although several sleep measures moved in the expected direction, none differed significantly from baseline or placebo, and where differences did reach significance for NREM and stage 2 sleep, the same differences already existed at baseline

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