Hormonal imbalances, particularly reductions in cytokinin and auxin levels, lead to stunted growth and leaf curling
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However, it should be noted that the genetics underlying clozapine-induced neutropenia are likely multifactorial and that having these genetic variants does not preclude initiation of the drug
Most notable were genes associated with TJ complexes, those facilitating drug efflux or the active transport of key nutrients, and BBB-enriched immune response genes (Fig