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PMID: 31735792 5 Megaloblastic Anemias: Nutritional and Other Causes

And a naturally occurring copper peptide called GHK-Cu might be exactly that signal

The marked Egr1 and Vegfr2 upregulation suggests that BPC 157 has vascularisation properties, and this mechanism likely underlies its ability to modulate ischemia/reprofusion injury

doi: 10.1128/JB.00883-10 144 JosephB.SchwarzR