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51 Dihexa mechanism of action suggests potential for enhancing the mind-muscle connection

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In conclusion, our study revealed a novel mechanism of neuronal injury induced by chronic hypoxia, highlighted the role of -syn phosphorylation in this process, and provided a potential new target for the intervention of chronic hypoxia injury

The mechanism appears to involve increased serotonin synthesis in substantia nigra (both compacta and reticulata), a regional pattern unlike any existing antidepressant drug, plus potential dopaminergic contributions given the nigrostriatal location