It is currently unknown whether these observations in mice will extend to humans, but Harris speculates that this may explain why some individuals acquire gray hair early in life
Curr Drug Targets Inflamm Allergy
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(2014) Fructose-1,6-bisphosphatase opposes renal carcinoma progression, Nature , 513 , 251-255, doi: Anderton, B., Camarda, R., Balakrishnan, S., Balakrishnan, A., Kohnz, R
However, for individuals actively managing complex, reactive chronic illnesses like Long COVID, ME/CFS, or severe dysautonomia, such high starting doses are rarely recommended due to the high potential for gastrointestinal upset or rapid, uncomfortable detoxification reactions (often referred to as a Herxheimer reaction)
This is where naturopathic care excelstreatments are not viewed in isolation but as part of the bigger picture, supporting physical, emotional, and lifestyle balance