Genome-wide methylation analyses of samples collected from the same diabetic patients 1617 years apart revealed that key genomic loci associated with diabetic complications of DNA methylation persist over time
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The hypothalamus modulates pulsatile gonadotropin-releasing hormone (GnRH) secretion, which governs pituitary release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH)
However, methotrexate therapy requires careful monitoring due to its potential for adverse effects, particularly hepatotoxicity (Malaviya 2016
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