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doi:10.5740/jaoacint.18-0045

It is studied for effects on glucose metabolism, mitochondrial efficiency, and NAD+-dependent pathways

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Factors such as the form of B12 used, additional ingredients, and manufacturing standards should be considered

Published studies primarily focus on its interaction with enzymatic and metabolic pathways rather than endocrine signaling systems

Intrinsic Factor and B12 Absorption: Vitamin B12 is a very large molecule compared to other vitamins and requires an enzyme called intrinsic factor to metabolize effectively